Lesley Brown completed a degree in biological science at Leeds Metropolitan University and following this completed a PhD investigating ethno-cultural differences in response to Transcutaneous Electrical Nerve Stimulation (TENS). This study included undertaking research in the UK and in Hong Kong. After this Lesley managed a research project at the Friarage Hospital in Northallerton investigating different physiotherapy treatment pathways for people with low-back pain.
Lesley has worked in the Academic Unit for Ageing and Stroke Research since 2011, working across a range of projects including a study investigating the use of screening tools to identify people with mild cognitive impairment. Lesley has contributed to Cochrane Systematic Reviews: Information provision for stroke patients and their caregivers; Physical rehabilitation for older people in long term care; Medical day hospital care for the elderly versus alternative forms of care.
Lesley is currently a senior research fellow and theme manager for the NIHR Applied Research Collaboration Yorkshire & Humber Older Peoples theme. Lesley manages the Community Ageing Research Study 75+ (CARE75+) study, a national longitudinal cohort study of older people.
Coventry PA, McMillan D, Clegg, A, Brown L, van der Feltz-Cornelis C, Gilbody S, Ali S. Frailty and depression predict instrumental activities of daily living in older adults: A population-based longitudinal study using the CARE75+ cohort. PLOS one, 2020;15(12), p.e0243972.
Brown L, Mossabir R, Harrison N, Brundle C, Smith J, Clegg A. Life in lockdown: A telephone survey to investigate the impact of COVID-19 lockdown measures on the lives of older people (≥ 75years). Age Ageing 2020; afaa255, https://doi.org/10.1093/ageing/afaa255
Farrow M, Biglands J, Tanner SF, Clegg A, Brown L, Hensor EMA, O’Connor P, Emery P, Tan AL. The effect of ageing on skeletal muscle as assessed by quantitative MR imaging: an association with frailty and muscle strength. Aging Clinical and Experimental Research 2020. https://doi.org/10.1007/s40520-020-01530-2
Jacob I, Mahmood F, Brown L, Heaven A, Mahmood S, Clegg A. Recruiting older people from the Pakistani community in Community Ageing Research 75+. British Journal of Community Nursing 2020;25(3):110–113 https://doi.org/10.12968/bjcn.2020.25.3.110
Crocker TF, Ozer S, Brown L, Hall J, Forster A. Non‐pharmacological interventions for longer‐term stroke survivors or their carers: an overview of Cochrane Reviews. Cochrane Database of Systematic Reviews 2019, Issue 4. Art. No.: CD013317. DOI: 10.1002/14651858.CD013317.
Brown L, Young J, Teale E, Santorelli G, Clegg A. A Cross-Sectional Study of the Impact of Pain in Older People with Frailty: Findings from the Community Ageing Research 75+ (CARE75+) Study. Advances in Geriatric Medicine and Research 2019;1:e190002. https://doi.org/10.20900/agmr20190002
Crocker TF, Brown L, Clegg A, Farley K, Franklin M, Simpkins S, Young J. Quality of life is substantially worse for community-dwelling older people living with frailty: systematic review and meta-analysis. Quality of life research 2019;28:2041–2056. https://doi.org/10.1007/s11136-019-02149-11
Brundle C, Heaven A, Brown L, Teale E, Young J, West R, Clegg A. Convergent validity of the electronic frailty index. Age Ageing 2019;48(1):152-156.
Heaven A, Brown L, Young J, Teale E, Hawkins R, Spilsbury K, Mountain G, Young T, Goodwin V, Hanratty B, Chew-Graham C, Brundle C, Mahmood F, Jacob I, Daffu-O’Reilly A, Clegg A. Community ageing research 75+ study (CARE75+): an experimental ageing and frailty research cohort. BMJ Open 2019;9(3):e026744. doi: 10.1136/bmjopen-2018-026744
Brown L, Heaven, Young J, Clegg A. (2017). The importance of oversight in Trials within Cohorts (TwiCs): experiences from the Community Ageing Research 75+ (CARE 75+) study: in Relton, C et al. (2017, June) The ethics of ‘Trials within Cohorts’(TwiCs): 2nd international symposium. In Trials (Vol. 18, No. 2, p. 244). BioMed Central.
Heaven A, Brown L, Foster M, Clegg A. (2016). Keeping it credible in cohort multiple Randomised Controlled Trials: the Community Ageing Research 75+ (CARE 75+) study model of patient and public involvement and engagement. Research Involvement and Engagement, 2(1), p.30.
Brown L, Forster A, Young J, Crocker T, Benham A, Langhorne P, Day Hospital Group. Medical Day Hospital Care for Older People versus Alternative Forms of Care. Cochrane Database of Systematic Reviews 2015, Issue 6. Art. No.: CD001730. DOI: 10.1002/14651858.CD001730.pub3
Brown L, Young J, Clegg A, Heaven A. (2015). Pain in older people with frailty. Reviews in Clinical Gerontology.
Crocker T, Young J, Forster A, Brown L, Ozer S, Greenwood D. (2013). The effect of physical rehabilitation on activities of daily living in older residents of long-term care facilities: systematic review with meta-analysis. Age and Ageing. 42, 682-8.
Crocker T, Forster A, Young J, Brown L, Ozer S, Smith J, Green J, Hardy J, Burns E, Glidewell E, Greenwood D. Physical rehabilitation for older people in long-term care. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD004294. DOI: 10.1002/14651858.CD004294.pub3.
Brown L, Tashani, O, Holmes M, Jones A. (2013). Ethno-Cultural Differences in Response to Acu-TENS on Experimentally Induced Pain: A Pilot Comparison between White British Students in the UK and Chinese Students in Hong Kong. Pain and Rehabilitation, the Journal of Physiotherapy Pain Association, (34), 5-12.
Forster A, Brown L, Smith J, House A, Knapp P, Wright J, Young J. Information provision for stroke patients and their caregivers. Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD001919. DOI: 10.1002/14651858.CD001919.pub3.
Brown L, Holmes M, Jones A. (2009). The application of Transcutaneous Electrical Nerve Stimulation (TENS) to acupuncture points (Acu-TENS) for pain relief: A discussion of efficacy and potential mechanisms. Physical Therapy Reviews.14 (2), 93-103.
Brown L, Tabasam G, Bjordal J, Johnson M. (2007). An investigation into the effect of electrode placement of transcutaneous electrical nerve stimulation (TENS) on experimentally induced ischemic pain in healthy human participants. The Clinical Journal of Pain, 23(9), 735-743.