Dr David Clarke

Associate Professor in Stroke Care


ORCID: 0000-0001-6279-1192

David is an Associate Professor in Stroke Care, and is a nurse by background. David is a qualitative researcher with an interest in ethnographic methods. David was Project Manager for the NIHR funded project Process Evaluation Embedded within a Randomized Controlled Trial of Caregiver Training after Stroke [TRACS], a large scale qualitative evaluation undertaken in 10 stroke units in England. A three year Stroke Association Senior Research Training Fellowship, awarded in September 2010 has recently been completed. The programme of research was focused on the practice of nurses in stroke rehabilitation units. David is Programme Manager for the Post Graduate Certificate in Stroke Care (Distance Learning) and a Member of the UK Clinical Research Network Primary Care Clinical Studies Group (Stroke).

Recent Funding Awarded

Forster A, Clarke D, Birch K, Carter G, Holloway I, Oxley S, Farrin A, Patel A, English C, Mead G, Lawton R. Development and evaluation of strategies to reduce sedentary behaviour in patients after stroke and improve outcomes. NIHR, Programme Grants for Applied Research £3,013,121; 01/10/2017-31/09/2024 (84 months).

Clegg A, Goodwin V, Young J, Forster A, Farrin A, Hartley S, Hulme C, Clarke D, Cundill B, Wright P. Randomised controlled trial evaluation to determine the clinical and cost effectiveness of a Home-based exercise intervention as Extended Rehabilitation in Older people with frailty following acute illness or injury, including internal pilot and embedded process evaluation (HERO). NIHR HTA £2,038,930.19; 01/03/2017- 31/05/2021 (51 months).

Clegg A, Young J, Forster A, Farrin A, Hartley S, Hulme C, Clarke D, Wright P, Cundill B. Randomised controlled trial evaluation to determine the clinical and cost effectiveness of a Home-based exercise intervention as Extended Rehabilitation in Older people with frailty following acute illness or injury, including internal pilot and embedded process evaluation (HERO). NIHR HTA £2,038,930.19; 01/03/2017- 31/05/2021 (51 months).

Jones F, Clarke D, Robert G, McKevitt C, Harris R, Cloud G, McDonald A. Using co-production to improve patient carer and staff experiences in health care organizations: a multi-centre, mixed methods evaluation in inpatient stroke units. NIHR HS&DR Programme £680,808.24, 01/01/2016-31/12/2018.

Clarke DJ, Forster A, Rodgers H, Tyson S, Drummond A, Palmer R, Prescott M. ReAcT: Why do stroke patients not receive the recommended amount of therapy? NIHR RfPB, £346,189; 01/09/2014-28/02/2017.

Recent Publications

Coleman S, Wray F, Hudson K, Forster A, Conroy S, Tremyl J, Shenkin SD, Nixon J, Fader M, Goodwin VA, Woods D, Crossland S, Holt R, Mcgregor L, Maud R, Wyrko Z, Lamb SE, Teale E. Using consensus methods to prioritize modifiable risk factors for development of manifestations of frailty in hospitalized older adults. Nursing Open 2023;10(2):1016-1028. https://doi.org/10.1002/nop2.1370

Wray F, Coleman S, Clarke D, Hudson K, Forster A, Teale, E. Risk factors for manifestations of frailty in hospitalized older adults: A qualitative study. Journal of Advanced Nursing 2022;78(6):1688– 1703. https://doi.org/10.1111/jan.15120

Johansson JF, Lam N, Ozer S, Hall J, Morton S, English C, Fitzsimons C, Lawton R, Forster A, Clarke D. A Systematic Review of Process Evaluations of Interventions in Trials Investigating Sedentary Behaviour in Adults. BMJ Open 2022;12(1) e053945; http://dx.doi.org/10.1136/bmjopen-2021-053945

Morton S, Hall J, Fitzsimons C, Hall J, English C, Forster A, Lawton R, Patel A, Mead G, Clarke DJ. A qualitative study of sedentary behaviours in stroke survivors: non-participant observations and interviews with stroke service staff in stroke units and community services. Disability and Rehabilitation 2021;44(20):5964-5973. https://doi.org/10.1080/09638288.2021.1955307

Hall JF, Corepal R, Crocker TF, Lam N, Burton LJ, Birch K, Carter G, Clarke DJ, English C, Farrin AJ, Fitzsimons C, Hall J, Holloway I, Ozer S, Lawton R, Mead G, Morton S, Patel A, Forster A. 2021. A systematic review and meta-analysis of non-workplace interventions to reduce time spent sedentary in adults. MedRxiv 2021; https://doi.org/10.1101/2021.05.27.21256673

Wray F, Clarke D, Cruice M, Forster A. Development of a self-management intervention for stroke survivors with aphasia using co-production and behaviour change theory: An outline of methods and processes. PLoS One 2021;16(11):e0259103. https://doi.org/10.1371/journal.pone.0259103

Prescott M, Lilley-Kelly A. Cundill B, Clarke D, Drake S, Farrin AJ, Forster A, Goodwin M, Goodwin VA, Hall AJ, Hartley S, Holland M, Hulme C, Nikolova S, Parker C, Wright P, Ziegler F, Clegg A. Home-based Extended Rehabilitation for Older people (HERO): study protocol for an individually randomised controlled multi-centre trial to determine the clinical and cost-effectiveness of a home-based exercise intervention for older people with frailty as extended rehabilitation following acute illness or injury including embedded process evaluation. Trials 2021;22(783). https://doi.org/10.1186/s13063-021-05778-5.

Hall J, Morton S, Hall J. Clarke DJ, Fitzsimons CF, English C, Forster A, Mead GE, Lawton R. A co-production approach guided by the behaviour change wheel to develop an intervention for reducing sedentary behaviour after stroke. Pilot Feasibility Studies 2020; 6:115 https://doi.org/10.1186/s40814-020-00667-1

Hall J, Morton S, Fitzsimons CF, Hall JF, Corepal R, English C, Forster A, Lawton R, Patel A, Mead G, Clarke DJ. Factors influencing sedentary behaviours after stroke: findings from qualitative observations and interviews with stroke survivors and their caregivers. BMC Public Health 2020;20:967. https://doi.org/10.1186/s12889-020-09113-6

Hall JF, Crocker TF, Clarke DJ. Forster A. Supporting carers of stroke survivors to reduce carer burden: development of the Preparing is Caring intervention using Intervention Mapping. BMC Public Health 2019, 19:1408; doi:10.1186/s12889-019-7615

Rawlings G, Willliams R, Clarke D, English C, Fitzsimons C, Holloway I, Lawton R, Mead G, Patel A, Forster A. Exploring adults’ experiences of sedentary behaviour and participation in non-workplace interventions designed to reduce sedentary behaviour: a thematic synthesis of qualitative studies. BMC Public Health 2019; 19:1099 doi:10.1186/s12889-019-7365-1.

Wray F, Clarke D, Forster A. How do stroke survivors with communication difficulties manage life after stroke in the first year? A qualitative study. International Journal of Language and Communication Disorders 2019;54(5). doi.org/10.1111/1460-6984.12487

Morton S, Fitzsimons C, Hall J, Clarke D, Forster A, English C, Chastin S, Birch KM, Mead G. Sedentary behavior after stroke: A new target for therapeutic intervention. International Journal of Stroke 2019;14(1):9-11. doi: 10.1177/1747493018784505.

Graham L, Cicero R, Clarke D, Cundill B, Ellwood A, Farrin A, Fisher J, Goodwin M, Hawkins R, Hull K, Hulme C, Trépel D, Williams R, Forster A. PATCH: posture and mobility training for care staff versus usual care in care homes: study protocol for a randomised controlled trial. Trials 2018;19(1):521. doi.org/10.1186/s13063-018-2863-5

Clarke DJ, Burton L, Tyson SF, Rodgers H, Drummond A, Palmer R, Hoffman A, Prescott M, Tyrrell P, Brkic L, Grenfell K, Forster A. Why do stroke survivors not receive recommended amounts of active therapy? Findings from the ReAcT study, a mixed-methods case-study evaluation in eight stroke units. Clinical Rehabilitation 2018;32(8): 1119-1132. doi.org/10.1177/0269215518765329

Sadler E, Hawkins R, Clarke DJ, Godfrey M, Dickerson J, McKevitt C. Disciplinary power and the process of training carers on stroke units. Sociology of Health and Illness 2018. 40(1):100-114. doi.10.1111/1467-9566

Wray F, Clarke DJ, Forster A. Post-stroke self-management interventions: a systematic review of effectiveness and investigation of the inclusion of stroke survivors with aphasia. Disability and Rehabilitation 2018;40(11):1237-1251. doi.org/10.1080/09638288.2017.1294206

Clarke D, Jones F, Harris R, Robert G, Collaborative Rehabilitation Environments in Acute Stroke (CREATE) team. What outcomes are associated with developing and implementing co-produced interventions in acute healthcare settings? A rapid evidence synthesis. BMJ Open 2017;7(7):e014650.doi: 10.1136/bmjopen-2016-014650.

Wray F, Clarke D. Longer-term needs of stroke survivors with communication difficulties living in the community: a systematic review and thematic synthesis of qualitative studies BMJ Open 2017;7(10):e017944.

Clarke D, Drummond A, Burton L, Tyson S, Rodgers H, Palmer R, Grenfell K, Prescott M, Forster A. What factors influence the provision of therapy to stroke survivors? Findings from an in-depth qualitative case-study series in eight stroke units. International Journal of Stroke 2016;11(Supp3):35.

Clarke DJ, Forster A. Improving post-stroke recovery: the role of the multidisciplinary health care team. Journal of Multidisciplinary Healthcare. 2015;8:433–442.

Clarke DJ, Tyson S, Palmer R, Drummond A, Rodgers H, Forster A, Burton L, Brkic L, Grenfell K, Tyrrell P, Prescott M. Why do patients with stroke not receive the recommended amount of active therapy (ReAcT)? Study protocol for a multisite case study investigation BMJ Open 2015;5(8) e008443 doi:10.1136/bmjopen-2015-008443.

Clarke DJ, Holt J. Understanding nursing practice in stroke units: a Q-methodological study. Disability and Rehabilitation. Disability and Rehabilitation 2014;21:1-11.

Clarke DJ, Hawkins R, Sadler E, Harding G,McKevitt C, Godfrey M, Dickerson J,Farrin AJ,Kalra L, Smithard D. Forster A.Introducing structured caregiver training in stroke care: findings from the TRACS Process Evaluation study. BMJ Open 2014;4(4):e004473. DOI:10.1136/bmjopen-2013-004473.

Clarke DJ. Nursing practice in stroke rehabilitation: systematic review and meta-ethnography. Journal of Clinical Nursing. In Press. Accepted February 2013.

Clarke DJ, Godfrey M, Hawkins R, Sadler E, Harding G, Forster A, McKevitt C, Dickerson J, Farrin A. Implementing a training intervention to support caregivers after stroke: a process evaluation examining the initiation and embedding of programme change. Implementation Science 2013, 8:96. DOI: 10.1186/10.1186/1748-5908-8-96.

Clarke DJ. The role of multidisciplinary team care in stroke rehabilitation. Progress in Neurology and Psychiatry. 2013:17(4): 5-8. Doi:10.1002/pnp.288.

Clarke DJ, Hawkins R, Sadler E, Harding G, Forster A, McKevitt C, Godfrey M, Dickerson J, Farrin A. Interdisciplinary Health Research: perspectives from a process evaluation research team. Quality in Primary Care 2012; 20(3):179-189.

Henshaw AM, Clarke DJ, Long AF. Midwives and supervisors of midwives’ perceptions of the statutory supervision of midwifery within the United Kingdom: A systematic review. Midwifery 2011; doi:10.1016/j.midw.2011.11.004.

Clarke DJ. Achieving teamwork in stroke units: the contribution of opportunistic dialogue. Journal of Interprofessional Care 2010; 24 (3):285–297.