Oly is a doctor specialising in the care of older adults. His research focuses primarily on improving the management of hypertension in later life, and the use of big data and artificial intelligence to improve care of older adults. Oly’s research is based in Bradford. Currently, he works clinically as a registrar at St James’s Hospital, Leeds Teaching Hospitals NHS Trust
Recent Funding Awarded
Todd O. Stratified hypertension management in later life: establishment of cohort linkage between ambulatory blood pressure measurements and routine health and social care data in Connected Bradford at University of Leeds. The Academy of Medical Sciences £29,472.50; 01/09/2022 to 01/12/2023.
Todd O, Hall M, Gale CP, Clegg AP. Does frailty modify the association of Blood Pressure and Outcomes in the Canadian Longitudinal Ageing Study Cohort British Geriatrics Society Specialist Registrar Start Up Grant (£2,858) 04/2018 –
Todd O, Young J, Hall M, Gale CP, Clegg AP. Can frailty inform the management of hypertension in in older people? (£192,301)
Dunhill Medical Trust Research PhD Training Fellowship. 10/2017 – 12/2020
Todd O, Flanagan KF. Does CMV affect the immunogenicity of BCG vaccination in Gambian infants? Elective at the Medical Research Council (UK), Fajara, The Gambia. Wellcome Trust Elective Grant (£1600); Pathology Society (£1200); Hammersmith Hospitals Elective Trust Fund (£500). 07/2007 – 09/2007
Publications
Platt JR, Todd OM, Hall P, Craig Z, Quyn A, Seymour M, Braun M, Roodhart J, Punt C, Christou N, Taieb J, Karoui M, Brown J, Cairns DA, Morton D, Gilbert A, Seligmann JF. FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty. ESMO Open 2022;8(1):100642. https://doi.org/10.1016/j.esmoop.2022.100642
Summerfield C, Smith L, Todd O, Renzi C, Lyratzopoulos G, Neal RD, Jones D. The Effect of Older Age and Frailty on the Time to Diagnosis of Cancer: A Connected Bradford Electronic Health Records Study. Cancers 2022; 14(22):5666. https://doi.org/10.3390/cancers14225666
George G, Fricker M, Todd OM, Makowa D, Tembo C, Dotchin C, Gray WK, Walker RW, Mbwele B, Paddick SM (2022) Screening for delirium and dementia in older hospitalised adults in Zambia. Journal of the Neurological Sciences 2022. https://doi.org/10.1016/j.jns.2022.120186. Epub 2022
Wilkinson C, Wu J, Clegg A, Nadarajah R, Rockwood K, Todd O, Gale CP. Impact of oral anticoagulation on the association between frailty and clinical outcomes in people with atrial fibrillation: Nationwide primary care records on treatment analysis. EP Europace 2022;24(7)1065–1075 https://doi.org/10.1093/europace/euac022
Todd OM, Clegg A. Prognostic tools for the care of older adults presenting with trauma. Age and Ageing 2021. afab249, https://doi.org/10.1093/ageing/afab249
Evans NR, Todd OM, Minhas JS, Fearon P, Harston GW, Mant J, Mead G, Hewitt J, Quinn TJ, Warburton EA. EXPRESS: Frailty and Cerebrovascular Disease: Concepts and Clinical Implications for Stroke Medicine. International Journal of Stroke 2021. https://doi.org/10.1177/17474930211034331
Masoli JAH, Todd OM, Clark CE. Systolic blood pressure and outcomes in frail older adults. British Journal of Hospital Medicine 2021;82(5). https://doi.org/10.12968/hmed.2021.0181
Wilkinson C, Clegg A, Todd O, Rockwood K, Yadegarfar ME, Gale CP, Hall M. Atrial fibrillation and oral anticoagulation in older people with frailty: a nationwide primary care electronic health records cohort study. Age Ageing May 2021 50(3):772-779
Chawner M, De Biase S, Offord NJ, Todd O, Clegg A, Sayer AA, Witham MD. Do Exercise Programmes For Older People With Sarcopenia Or Frailty Deliver An Evidence-Based Service? Findings From A UK Survey. Age Ageing 2021;50(1): i12–i42.
Wilkinson C, Wu J, Searle SD, Todd O, Hall M, Kunadian V, Clegg A, Rockwood K, Gale CP. Clinical outcomes in patients with atrial fibrillation and frailty: insights from the ENGAGE AF-TIMI 48 trial. BMC Medicine 2020; 18:401. https://doi.org/10.1186/s12916-020-01870-w
Veenhuizen M, Todd O, Anand A, Whiteley W. How to design a hypertension treatment trial that informs care of older people with frailty: a survey of clinicians in Ireland and the UK Age Ageing 2020. afaa198, https://doi.org/10.1093/ageing/afaa198
Hale M, Zaman H, Mehdizadeh D, Todd O, Callaghan H, Gale CP, Clegg A. Association between Statins Prescribed for Primary and Secondary Prevention and Major Adverse Cardiac Events among Older Adults with Frailty: A Systematic Review. Drugs & Aging 2020; 37:787–799 https://doi.org/10.1007/s40266-020-00798-3
Headlam J, Wheeler A, Yuen K, Brierley E, Todd O. Disseminated Bacillus Calmette-Guerin (BCG): A cause of delirium in an older adult. Journal of the Royal College of Physicians Edinburgh 2020;50(2):152–155. https://doi.org/10.4997/JRCPE.2020.215
Witham MD, Chawner M, Biase S, Offord N, Todd O, Clegg A, Sayer AA. Content of exercise programmes targeting older people with sarcopenia or frailty – findings from a UK survey Journal of Frailty Sarcopenia & Falls 2020; 5(1):17-23. doi: 10.22540/JFSF-05-017
Sheppard J, Lown M, Burt J, Temple E, Lowe R, Ashby H, Todd O, Allen J, Ford GA, Fraser R, Heneghan C, Hobbs R, Jowett S, Little P, Mant J, Mollison J, Payne R, Williams M, Yu L, McManus RJ. Generalisability of blood pressure lowering trials to older patients: cross-sectional analysis. Journal of American Geriatrics Society 2020;68(11):2508-2515 https://doi.org/10.1111/jgs.16749
Todd OM, Burton JK, Dodds RM, Hollinghurst J, Lyons RA, Quinn TJ, Schneider A, Walesby KE, Wilkinson C, Conroy S, Gale CP, Hall M, Walters K, Clegg AP. New Horizons in the use of routine data for ageing research. Age Ageing 2020; afaa018, https://doi.org/10.1093/ageing/afaa018
Todd OM, Wilkinson C, Hale M, Wong NL, Hall M, Sheppard JP, McManus RJ, Rockwood K, Young J, Gale CP, Clegg A. Is the association between blood pressure and mortality in older adults different with frailty? A systematic review and meta-analysis. Age Ageing 2019;48(5):627-635. doi: 10.1093/ageing/afz072.
Witham MD, Roberts HC, Gladman J, Stott DJ, Aihie Sayer A, Aspray TJ, Brock P, Clegg A, Cox N, Ewan V, Frith J, Burton JK, Jackson T, Lewis EG, Lim SE, Makin S, Lochlainn MN, Richardson S, Shenkin SD, Steves CJ, Todd O, Tullo E, Walker R, Yarnall A. Extended Working Group* from the NIHR Newcastle Biomedical Research Centre Meeting. Growing research in geriatric medicine. Age Ageing. 2019 [online] doi: 10.1093/ageing/afy220
Wilkinson C, Todd O, Clegg A, Gale CP, Hall M. Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis. Age Ageing 2019;48(2)196–203. doi: 10.1093/ageing/afy180.
Teale EA, Siddiqi N, Clegg A, Todd OM, Young J. Non-pharmacological interventions for managing delirium in hospitalised patients. Cochrane Database of Systematic Reviews 2017(4):10 Apr 2017 doi 10.1002/14651858.CD005995.pub2
Todd OM, Gelrich L, MacLullich AM, Driessen M, Thomas C, Kreisel SH, (2017). Sleep Disruption at Home As an Independent Risk Factor for Postoperative Delirium. Journal of the American Geriatrics Society, doi 10.1111/jgs.14685
Todd OM, K Sikwewa, J Kamp, I Hodt Rasmussen, S Kudsk-Iversen, K Mortensen. (2015). Inadequate monitoring risks safety of blood transfusion in rural Zambia. International Symposium on Intensive Care and Emergency Medicine 19 Suppl 1 P338
O M Todd, A Heaven, E Teale, A Clegg. (2017). Poor Subjective Sleep quality associates variably with different frailty measures in cross-sectional study of community dwelling older people. British Geriatrics Society 2017 http://www.bgs.org.uk/abstracts/oup_spring2016.docx
Todd OM, Teale EA, (2017). Delirium: a guide for the general physician. Clinical medicine (London, England), 17 (1), pp. 48-53
Todd OM, Clegg AP, (2016). Moving upstream in the frailty trajectory. Age and ageing, 45 (4), pp. 438-9
Todd O, Clegg A, (2016). A Randomized Trial of Intensive versus Standard Blood-Pressure Control. The New England journal of medicine, 374 (23), pp. 2292
Kilgour AH, Todd OM, Starr JM, (2014). A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the lifecourse. BMC geriatrics, pp. 85