Bradford Ophthalmology Research Network (BORN)

Overview of the Research

Who We Are

We are one of the most experienced clinical research team engaged in eye and vision research in UK. Clinical research in ophthalmology in Bradford has a long tradition that was anchored in 2000 with collaborative studies on Photodynamic therapy for macular degeneration by consultant Ophthalmologist, Professor Faruque Ghanchi. This systematically evolved into the current Bradford Ophthalmology Research Network (BORN) with Sister Nicola Hawes joining the team as research nurse for multicentre clinical trial the IVAN study in 2008. The team now has 2 research nurses, a research associate practitioner, a research fellow, 2 research optometrists, and 5 accredited ophthalmic photographers.  BORN has increased the research portfolio, received high accolade (winner of a national award in 2016) and built a strong track record with international recognition.

BORN have facilitated over 30 clinical trials since 2008 and recruited over 500 participants to these trials. We have a diverse portfolio of studies, (phase II- IV) both industry sponsored and NIHR/academic portfolio studies.  We have developed a clinical research facility within the department of ophthalmology with state of the art clinical facilities at Bradford Teaching Hospitals NHS Foundation Trust (BTHFT). With a diverse patient population of over 0.5 million and a competent and committed specialist ophthalmology research team, we are well placed to deliver high quality clinical research to enhance scientific knowledge and improve our patient care  by facilitating access to more research programmes to our deserving patients.

Through our research and partnerships, the team has invested in new cutting edge equipment for the ophthalmology and macular clinics such as Multimodal retinal imaging Fluorescein and Indocyanine green angiography, Fundus Auto Fluorescence, Optical Coherence Tomography (OCT), OCT angiography, OPTOS wide field camera, Micro-Pulse Laser. All these and the CRF are complementing the clinical care delivered in the NHS at Bradford Teaching hospitals.

Mission Statement

  • To increase and improve research activity within Ophthalmology and embed it into everyday practice.
  • To promote science, education and innovation for clinical care for ophthalmology.
  • To make research common practice, that is valued by all and available to all.
  • To value patients and their contribution to clinical research and provide safe, quality care
  • To be role models within Ophthalmology and promote best practice when caring for patients with ophthalmological conditions

 

Our main priorities are acting in the best interests of our patients, Quality of care and safety within ophthalmic research. Our success as a research team is due to our patients who have kindly volunteered to help with our research projects over the years.

Contact Us

Interested in getting involved with ophthalmic research?

Contact Nicola Hawes or Sarah Moss :
E: Nicola.hawes@bthft.nhs.uk sarah.moss@bthft.nhs.uk
P: 01274 27 6376 / 01274 27 6377 / 0127427 6378
M: 07976 447 574

Follow us on Twitter @BTHFTeye_res

The Research Team

Prof Faruque Ghanchi

Consultant Ophthalmologist

Miss Helen Devonport

Miss Helen Devonport

Consultant Ophthalmologist

Miss Roopa Setty

Miss Roopa Setty

Consultant Ophthalmologist

Mr Murtuza Mookhtiar

Consultant Ophthalmologist

Mr Zeid Madanat

Research Fellow

Dr Charlotte Hazel

Research Optometrist

Dr Corinne Fulcher

Research Optometrist

Miss Farhat Butt

Senior Ophthalmology Registrar

Nicci Hawes

Lead Research Nurse

Sarah Moss

Research Nurse

Hayley Barker

Hayley Barker

Research Associate Practitioner

Lorraine Terry

Lorraine Terry

Clinical Trials Assistant

Our Research 

LATEST RESEARCH

Current Research

DRAKO – Observational study of patients treated with Aflibercept for Diabetic Macular Oedema

PANDA-2 – Conbercept vs Aflibercept in patients with Wet Age Related Macular Degeneration

RHINE – Faricimab vs Aflibercept in patients with Diabetic Macular Oedema

TENAYA – Faricimab vs Aflibertcept in patients with Wet Age Related Macular Degeneration

RAPTOR – Brolicizumab vs Aflibercept in patients with Branch Retinal Vein Occlusion

Industry Partners

Alcon

Allergan

Bayer

Clearside

Novartis

Oraya

pSivida

Santen

Roche

Bioeq GmbH

SYNEOS Health

O4 Research

Covance

Iqvia

Achievements

Over the past 9 years in research we have had a number of accolades:

  • Bayer Ophthalmology Judge’s Special Award December 2016 for innovation and determination in developing a strong ophthalmology research team
  • 1st Global Patient for Constance study 2012
  • 1st rest of world patient for pSivida, 2014
  • 1st Uk patient for proxima B 2015
  • Fastest recruiter in UK (within a week) for the Polaris Study, 2013
  • Top recruiting site (UK) October 2015 – LEAVO study
  • 1st UK patient RHINE (2018)
  • 1st Rest of World patient TENAYA (2019)
  • Fastest and Highest recruitment in the UK TENAYA (2019)

Other achievements, e.g., radio/TV appearances/newspaper articles include any publications

http://www.thetelegraphandargus.co.uk/news/11831689.State_of_the_art_eye_scanner_cements_hospital_s_place_at_forefront_of_eye_research/

http://www.thetelegraphandargus.co.uk/news/health/11099506.Pioneering_implant_trial_could_transform_lives/

http://www.thetelegraphandargus.co.uk/news/9700177.Drugs_trial_could_save_NHS___84m/

http://www.thetelegraphandargus.co.uk/news/13325587.Volunteers_sought_for_ground_breaking_research_in_Bradford_into_condition_causing_blindness/

http://www.thetelegraphandargus.co.uk/news/13592924.Dedicated_eye_treatment_volunteer_celebrates_90th_birthday_in_research_unit/

Ghanchi FD, Hazel CA. South Asian Diabetic Macular Oedema treated with Ranibizumab (ADMOR) – http://www.nature.com/eye/journal/vaop/ncurrent/full/eye2015209a.html

Fulcher C, McGraw PV, Roach NW, Whitaker D, Heron J. Object size determines the spatial spread of visual time. In: Proc. R. Soc. B 2016 Jul 27 (Vol. 283, No. 1835, p. 20161024). The Royal Society.

HISTORICAL RESEARCH

Previous Research:

VPDT, IVAN, COMRADE B, COMRADE C, SAKURA, INTREPID, POLARIS, IVAN B, SAFARI, LUMINOUS< ASH< CONSTANCE, INJECT, DREAMS, pSIVIDA, LEAVO, SPECTRI, PROXIMA B, OMASPECT, EDNA, COLUMBUS, CENTERA, VICI, FASBAT, OCTANE, EMERALD, DIAMONDS